A study published recently in Obstetrics and Gynecology evaluated uterine evacuation of patients with molar pregnancy, comparing manual with electric vacuum aspiration. Of 1,727 patients with molar pregnancy, 1,206 underwent electric vacuum aspiration and 521 underwent manual vacuum aspiration. Following human chorionic gonadotropin normalization, patients with benign molar pregnancy were followed for 6 months and patients treated for gestational trophoblastic neoplasia were followed for 12 months. Uterine synechia were found to develop less frequently after manual vacuum aspiration than after electric vacuum aspiration (6 of 521 vs 63 of 1,206) despite no differences in the occurrence of incomplete uterine evacuation (65 of 521 vs 161 of 1,206) development of postmolar gestational trophoblastic neoplasia (90 of 521 vs 171 of 1,206) or the need for multiagent chemotherapy (22 of 521 vs 41 of 1,206). Manual vacuum aspiration thus seemed to be similar to electric vacuum aspiration for treatment of molar pregnancy and could possibly be associated with less development of uterine synechia.